why isn t my semaglutide working anymore Am I Not Losing Weight on Semaglutide: Medical Causes Explained The Top Four Reasons Wegovy

Instead of getting a semaglutide injection plus a separate B12 injection, patients receive both in one shot

Common reasons for switching include inadequate weight loss response after 46 months, intolerable nausea or vomiting, constipation that doesn't resolve with dietary changes, or a desire to explore medications with different mechanismssuch as switching from a GLP-1-only agent to a dual GLP-1/GIP agonist

doi: 10.1152/physrev.00039.2016 406 ReardonCMurrayKLomaxAE

doi: 10.3390/nu12082333, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 59.Larrieu T, Laye S

However, semaglutide reduces appetite and food intake, which *could* indirectly impact caloric intake and nutrient absorptionfactors that support milk production