Results SIRT3 suppresses HSC response to classic trained immunity, acute inflammation and tissue functional decline To determine whether SIRT3 regulates HSC response to classic trained immunity induction, we crossed Cre-inducible Sirt3 -overexpressing mice with Mx1-Cre mice to generate mice that overexpress SIRT3 in the hematopoietic system (Mx1-T3) (Extended Data Fig
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Across age groups, current GLP-1 use is highest among those who are between the ages of 50 and 64 (22%), with smaller shares of those ages 18-29 (4%), 30-49 (11%), or over age 65 (9%) saying they are currently using these drugs
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