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(3) if there is maladaptation, the organism is marked by the accumulation of products of biological activity

doi: 10.1212/WNL.0b013e3182a8236e 69 RamaniA.MllerL.OstermannP

These approaches enable systematic analysis of immune cell dynamics, cellcell interactions, and pathologic microenvironments within tissues, leading to a more comprehensive understanding of inflammatory phenotypes (Figure 6B) ( in silico pre-screening of natural products, with top candidate compounds subsequently validated in human organoidzebrafish chimera models

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