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doi: 10.1016/j.molcel.2023.11.001 2

Talk to your prescriber if you experience joint pain as a side effect

Higher cortical porosity leads to lower bone strength and a higher incidence of fragility fractures in this population

LOXs and/or cytochrome P450 oxidoreductases (PORs) have been shown to initiate lipid peroxidation through lipid deoxygenation [5, 50, 51]

The broader picture is that the next generation of obesity treatments involves multi-target approaches, whether through single molecules activating multiple receptors (tirzepatide, retatrutide, survodutide, mazdutide) or through combination therapies pairing separate compounds (CagriSema)