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The new label includes references to some of those postmarketing risks, including intestinal obstruction, [and] severe constipation including fecal impaction. Some patients who took Zepbound have filed lawsuits, accusing Eli Lilly of failing to properly warn them that Zepbound could increase their risk of severe gut problems, including bowel obstructions, pancreatitis, and gastroparesis

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This combination aims to leverage the pharmacokinetic profiles of both esters to provide a more stable and sustained release of testosterone, potentially reducing the frequency of injections and minimizing fluctuations in hormone levels

Despite the official declaration, and resulting changes in treatment protocols, the idea that being overweight is somehow a moral failing lingers in the culture