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Profile 5: Pediatric and Adolescent Patients Under 18 Wegovy received FDA approval for chronic weight management in adolescents aged 12 and older in December 2022, based on the STEP TEENS trial (N=201, semaglutide 2.4 mg weekly, 68 weeks, mean BMI reduction of 16.1% vs

Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (Mounjaro) and chronic weight management (Zepbound)

Lu et al., 2018

Under normal conditions, their contents and distributions are in dynamic equilibrium, which is vital for cell survival [51]