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These effects make GLP-1 a powerful tool in managing weight and blood sugar levels, which is why it has become a focal point in the development of medications for diabetes and obesity

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Severe gastrointestinal intolerance Some researchers experience debilitating nausea and vomiting that does not improve with standard titration

To date, it is not known if the benefits of treatment with GLP-1 RAs are direct or mediated by drug-induced weight loss