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Capsaicin receptor VR1 and ATP-gated ion channel P2X3 in human urinary bladder

Franco R, DeHaven WI, Sifre M, Bortner CD, Cidlowski JA

Understanding the caffeine and inflammation connection The short answer is that there is no one right answer to the question of Does caffeine cause inflammation? Thats because research shows that caffeine-containing beverages like coffee can have either pro- or anti-inflammatory effects (5), depending on the person drinking the caffeine

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A lack of B12 can cause nerve damage, leading to pain and numbness