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These short-lived effects are part of the cost of getting an injected therapy

NICE and the BNF provide clear guidance on appropriate use, emphasising that injections should be reserved for cases where oral supplementation is inadequate or inappropriate

33823377, 37083708, 36791631) In INH, gyromitra mushroom toxicity, or chronic oral hydralazine use, very high doses are used (e.g., 5 grams IV)

Its mechanism of action involves the direct inhibition of the transcription factor NF-B, a central regulator of the inflammatory response