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Prespecified subgroup analyses Subgroup analyses were conducted to examine variations in risk related to the desired outcomes among the GLP-1 RAs users

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& Nangaku, M

These effects are mediated through weight loss, enhanced insulin sensitivity, and direct hepatic actions such as activation of adenosine AMPK, which contributes to reduced hepatic lipid accumulation [247,248,249]

By enabling sustained release, targeted delivery, and improved bioavailability, these platforms offer promising strategies for enhancing therapeutic outcomes in metabolic diseases