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Three different mechanisms of GST-catalyzed isomerization are known: (i) carbon-carbon double bond shifts, (ii) intramolecular redox reactions and (iii) cis-trans isomerizations 21

"This drug belongs to the same broad class as Ozempic-style weight loss drugs, and it acts on multiple hormone pathways that are involved in appetite, metabolism and blood sugar," he said

FOXO4-DRI is an investigational compound with no completed human clinical trials

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The solution to these challenges is to ensure that the method has high precision and a broad analytical range