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Effect of parenteral selenium supplementation in critically ill patients: a systematic review and meta-analysis

Artemisinin activation is decreased in PfK13 mutant lines Artemisinin requires activation by free heme, thus we anticipated that the decrease in heme levels observed in 3-6 hpi ring-stage parasites would result in decreased artemisinin activation and, therefore, decreased activity

[4] In case of accidental large overdose (e.g., someone receives far more frequent injections than prescribed), monitoring for symptoms like flushing, tingling in extremities, or liver enzyme elevations would be prudent

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