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Probing position N108, we found that incorporation of any other amino acid resulted in a substantially reduced formation of cyanidin ( 8 ) suggesting that the hydrogen-bond interaction of the asparagine to the flavonoid substrate is critical for dehydratase activity, while GSH-transferase activity was comparatively less affected for N108 variants comprising an alanine, histidine, tyrosine or tryptophan (Fig

Stress Management Chronic stress increases oxidative stress, which depletes glutathione levels in the body[18]

The apoptosis index (AI) was calculated as described previously [12]

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