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doi: 10.1016/j.jff.2020.104172 421 DengHLiuJXiaoYWuJLJiaoR

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Key rotation principles include: Use a systematic rotation pattern and keep at least 12 cm from the previous site Avoid areas with lumps, bruises, scars, or skin changes Inspect injection sites regularly for any abnormalities Alternate between different body areas (abdomen, thighs, arms) when possible Maintain the recommended distance from the navel and other anatomical landmarks If you find lumps or skin changes , avoid those areas and discuss with your diabetes specialist nurse