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As clinical use of this medication increases, the findings call for additional studies to evaluate long-term effect on alcohol consumption, and the ideal doses and treatment durations, which may be different from the current recommendations for people living with diabetes and obesity

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MnSOD is the primary antioxidant that neutralizes highly reactive superoxide radicals (O2), which are primarily generated within mitochondrial membranes

Start with 0.25 mg/week for four weeks, then increase to 0.5 mg/week, and possibly up to 1 mg/week if needed

There's no mandatory washout period, though the transition should be managed by a clinician to handle the dose conversion and monitor for any changes in side effects