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FIGURE 1 The mechanism of GLP-1 RAs, however, is now understood to extend far beyond glucose control, offering powerful dual central and peripheral action

This protects the vital bioactive peptides which can support immune health and glutathione synthesis, like lactoferrin and serum albumin

Furthermore, macrophages contribute to immune cell recruitment, cytokine release, and airway remodeling in asthma, highlighting their role in both the exacerbation and resolution of inflammation [96]

[3] Based on data published to date including a Phase 2 obesity trial published in the New England Journal of Medicine (Jastreboff et al., 2023) and a Phase 2 type 2 diabetes trial published in The Lancet (Rosenstock et al., 2023) the most commonly reported side effects are gastrointestinal in nature

Hertrampf E, Cortes F