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Cardioprotective and Vasodilatory Actions of Glucagon-Like Peptide 1 Receptor Are Mediated Through Both Glucagon-Like Peptide 1 ReceptorDependent and Independent Pathways
In addition, Lf can also regulate cytokine synthesis by modulating gene expression (i.e., by blocking the NF-kB): in particular Lf down regulate the levels of some pro-inflammatory cytokines, such as interleukin 1, tumor necrosis factor (TNF-), interleukin 6 and interleukin 8 (Sabra and Agwa 2020), and it up regulate the production of anti-inflammatory interleukin 10 (IL-19) (Hwang et al
Abbreviation, -GCS, -glutamylcysteine synthetase
21 Sahay A, Epari S, Gupta P, et al