Medical monitoring is essential to track progress, address possible side-effects early, and make any necessary adjustments. Side effects are possible when starting GLP-1 medication, and can include nausea, diarrhoea and constipation
Protecting Muscle: The Key to Safe Menopause Weight Loss Because a GLP-1 lowers appetite, the biggest risk during menopause weight loss is losing muscle along with fat
Furthermore, in participants with T2D, treatment with the selective long-acting GIP receptor agonist, macupatide, was associated with a larger insulin sensitivity improvement compared with the selective GLP-1 receptor agonist dulaglutide, despite similar body weight reduction, and combination therapy with these agents was associated with additive effects on insulin sensitivity [20]
Su H, Lang B, Newman E
10.1038/ng.3405 76 KawamuraY.MatsuoH.ChibaT.NagamoriS.NakayamaA.InoueH.et al (2011)