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FIGURE 1 2.2 Pathogenesis 2.2.1 Effects of blue light on cornea and lens Research has shown that blue light toxicity is not limited to the retina, but can also damage the ocular surface through oxidative stress, inflammatory response, and cell apoptosis, and is associated with the formation of ocular surface inflammation and dry eye syndrome (Lee et al., 2016

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Body composition data from the SURMOUNT-1 trial of tirzepatide show that approximately 75% of the weight lost was fat mass and 25% was lean mass 2

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