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An environment-dependent transcriptional network specifies human microglia identity

(105) employed untargeted metabolomics and 16S rRNA gene sequencing to reveal significant alterations in serum metabolites and gut microbiota composition in DKD rats, primarily involving carbohydrate, lipid, and amino acid metabolism, with phenylalanine, tyrosine, and tryptophan metabolic pathways being significantly enriched

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