For example, GLP-1 analog drugs like Semaglutide can be tested for immunogenicity using the classical radioimmunoassay (RIA) method, which can better meet the requirements of global joint submissions for method consistency in clinical research
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
Now, two new late-phase clinical trials, sponsored by Eli Lilly and Company, suggest that transitioning from high dose injectable weight loss medications to either a daily pill or a lower maintenance dose can help people living with obesity to keep off most of the weight they have already lost The results of the ATTAIN-MAINTAIN and SURMOUNT-MAINTAIN trials were presented at the European Congress on Obesity and published in Previous research suggests that 1 year after stopping weight loss medication, people may regain, on average, 60% of their lost weight
"Xenical is indicated for obesity management, including weight loss and weight maintenance, when used in conjunction with a reduced-calorie diet and to reduce the risk for weight regain after prior weight loss," the FDA said
More serious concerns obviously warrant emergency medical attention, but routine support questions can pile up over weekends and create anxiety for newer patients