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The prolonged treatment durations ranging from several months to years may lead to poor patient compliance and dissatisfaction

While total cholesterol and LDL levels were reduced, there was no significant differences in HDL and triglycerides

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cerevisiae cells expressing tt SI-TGP 64 were solubilized in buffer containing 1%(w/v) DDM, 0.2%(w/v) CHS, 500 mM NaCl, 1 mM PMSF, 1 mM TCEP, 0.1 protease inhibitor cocktail, 2 mM imidazole, 50 mM Tris-HCl pH 8.0 at 4 C for 2 h with mild stirring