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For people whose weight challenges have a metabolic component, clinically supervised GLP-1 therapy represents a genuinely different tool than most have tried

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Visit our website terms of use and permissions pages at www.npr.org for further information

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He got people in nursing homes, two groups

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Semaglutide and other GLP-1 receptor agonists produce weight loss by slowing stomach emptying and reducing appetite signaling in the brain

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Zepbound is a prescription medication, also known by its active ingredient, tirzepatide, which received FDA approval specifically for chronic weight management in adults with obesity or those who are overweight with at least one weight-related condition

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