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Seek medical advice if you experience severe or worsening abdominal pain, persistent vomiting, signs of dehydration, blood in vomit or stools, severe constipation, or symptoms suggesting pancreatitis (severe upper abdominal pain radiating to the back)

Focus on areas with dullness, pigmentation, or uneven tone

The importance of selenocysteine comes from its role in gene expression and activity of the Se-dependent enzyme, GSH-Px (Floh et al., 1997

Cystinosin deficiency leads to impaired lysosomal clearance and disrupted endolysosomal trafficking, which in turn contributes to defective autophagy and altered proteostasis [144, 146, 147]

Thus, GSH is essential in maintaining cellular redox balance and preventing ferroptosis by supporting GPX4 in detoxifying lipid peroxides (Ursini and Maiorino, 2020)