Key points GLP-1 is a hormone that increases insulin release and prevents the release of too much glucagon, helping manage blood glucose levels in individuals with type 2 diabetes GLP-1 receptor agonists, such as liraglutide and semaglutide, effectively reduce blood glucose levels Semaglutide is more effective than liraglutide at reducing blood sugar levels Tirzepatide is a newer GLP-1 receptor agonist that also mimics the actions of another hormone called GIP, which can also reduce blood sugar levels A randomised controlled trial showed that tirzepatide led to more significant blood sugar reductions than semaglutide across three doses Tirzepatide may be more effective than semaglutide at higher doses, but this needs further investigation Liraglutide and semaglutide are available in the UK and the US, while tirzepatide is only available in the US but is likely to be approved in the UK soon
doi: 10.1016/S0140-6736(19)31775-1 [DOI] [PubMed] [Google Scholar] 143.Borges G, Bagge CL, Cherpitel CJ, et al
C oncentrate In our experience, electrolyte concentrate, or electrolyte drops, are good for home use but not necessarily for extended wilderness adventures (such as backpacking or bikepacking)
[Naltrexone] isnt only for people at or approaching rock bottom, says Sunnyside co-founder and CEO Nick Allen
Leiter LA, Bain SC, Bhatt DL, Buse JB, Mazer CD, Pratley RE, Rasmussen S, Ripa MS, Vrazic H, Verma S
