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Cell treatment and cell viability assay Neurons from the corresponding treatment groups were cultured in RPMI 1640 medium that contained 0.1 mM, 1 mM, 10 mM and 100 nM GLP-1(736), along with 10 M XMD8-92 (ERK5 inhibitor, cat

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They explain these findings by the fact that as the disease progresses the free radicals production is increased and the capacity of antioxidant systems is reduced

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