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We found that cisplatin treatment caused a decrease in mitochondrial biogenesis (PGC-1, NRF-1, TFAM, mtDNA, ND1), mitochondrial mass (Porin and Citrate synthase activity) and fusion index (MFN2, Drp1), together with changes in the expression of autophagy-related genes (AKT/FoxO pathway, Atg1, Beclin1, LC3AII, p62) and enhanced ROS production (PRX III, MnSOD)

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Are there any, you know, any folks who this isnt good for, you know, or as we say in the trade, contraindications are there, you know, whats the safety on it and such or, you know

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