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M-YL and H-YL: writingoriginal draft preparation

The assay based on the reaction of GSH with 5,5-dithio-bis-2-nitrobenzoic acid (DTNB) in the presence of glutathione reductase, was performed according to the protocol 56 and measured with a TECAN plate reader at 412 nm

A commenter expressed concern that the MIPS measures are too limiting, especially given CEHRT is already widely in use, and that it could unintentionally discourage adoption of remote patient monitoring or telemedicine tools, noting that patient engagement and interoperability are vital for value-based care and suggested that information blocking and HIPAA regulations offer more meaningful incentives

NAC also increases the activity of such enzymes as GR, which accelerates GSH regeneration [44]

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