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We also explored the mechanism by which NAC promotes doxycycline resistance in bacteria, which provides a theoretical basis for clinical drug administration contraindications

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found a similar trend in obese DM2 patient who underwent SG with EWL of 47% [51] The STAMPEDE trial showed more weight loss in BS group as compared to medical-therapy group after 1 year (RYGB 29.49.0 kg, SG 25.18.5 kg, medical therapy 5.48.0 kg, P 10 years 54%) lower diabetes severity (diet controlled) and lower central obesity have been associated with a higher DM remission rate [26, 62, 63] Patient with type 1 DM undergoing BS did had some minor improvement in HbA1c despite similar weight loss to patients with DM2 [62]

Tirzepatide is studied for its dual engagement of GLP-1 and GIP receptor signaling pathways rather than single-pathway activity