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Patients typically start with a lower dose to minimize Ozempic side effects, gradually increasing to a therapeutic dose (2 mg max dose/week) as directed by the healthcare provider

NSAIDs like ibuprofen can irritate the stomach lining directly, and combining this effect with semaglutide's slowed digestion may increase discomfort or nausea in some patients

Systemic Side Effects Gastrointestinal Side Effects The most commonly reported side effects of GLP-1 RAs are gastrointestinal, including nausea, vomiting, diarrhea, constipation, abdominal pain, and dyspepsia [113,114,115]

Morales DR, Bu F, Viernes B, et al