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The compound was first studied because researchers noticed the stomach has a remarkable ability to protect and repair its own lining, even sitting in a bath of acid that would burn most tissue

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Furthermore, treatment with lutein was found to promote the differentiation of SH-SY5Y cells, particularly enhancing the expression of microtubule-associated protein 2 and neuronal arborization, and the neuronal differentiation was possibly mediated via the regulation of PI3K pathway-induced mitochondrial respiration and signaling [77]