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MedChemExpress, HY-50767A) was dissolved in 10% DMSO, 40% PEG300, 5% Tween-80 and 45% saline and administered via oral gavage

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The anti-STR-CO-GNSs can attach to the cell membrane and eliminate the exteriors of bacterial cells, while STR can penetrate the cells and result in bacterial mortality

The paracellular transport of Ca 2+ in the TAL is driven by the electrochemical gradient that is established across the tubule via the actions of the apical transporters ROMK and NKCC2