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The high content of vardenafil however does not lead to an increase in any side effects unless the patient has taken an overdose

These individuals need supplementation and regular monitoring to prevent deficiency from developing over months to years of treatment

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[30] [28] Vitamin B 12 and folate status during pregnancy is associated with the increasing risk of low birth weight, [22] [31] preterm birth, [31] insulin resistance and obesity [21] [23] in the offspring