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Prolonged LC treatment elevates fasting plasma TMAO [16,17,18, 58, 59]

Urine output should be maintained at a level of 100 mL every four hours

Values were normalized to three housekeeping genes ( Actb , Rplp0 and Ppia ) using the C t method

Although lactylation modifications have been demonstrated to regulate ferroptosis across diverse experimental models, it remains unclear whether these mechanisms are restricted to the specific disease contexts and models studied or can be universally extended to all cellular systems

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