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Decisions about GLP-1 medications can add another layer and deserve clear information, honest discussion, and individualized support

Enhanced Nitric Oxide (NO) Production It has been shown to activate endothelial nitric oxide synthase (eNOS), improving vascular function and integrity

Beyond the GI profile, the NEJM Phase 2 trial also logged back pain as a low-rate adverse event across dose groups, and a small number of pancreatitis and gallbladder events were recorded at higher doses the full NEJM 2023 retatrutide obesity trial adverse events line-listing (abdominal pain, back pain, pancreatitis, gallbladder) is why many researchers pair the stomach pain discussion with back pain when reviewing the data

(PubMed) Yoritaka A, Kawajiri S, Yamamoto Y, et al

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