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doi: 10.1055/s-0031-1278316

Vitamin B6 : Supports neurotransmitter function and helps convert food into energy

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When mature IGF-I lacking any E-peptide extension was expressed virally, it failed to increase muscle mass, whereas the E-peptide-bearing IGF-IA and IGF-IB isoforms drove hypertrophy evidence that, in this system, the E-domain is necessary for the local anabolic effect rather than being an inert appendage