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Both acute GLP-1 infusion (65, 66) and a single liraglutide dose (67) decreased plasma ANG II concentration in healthy subjects and type 2 diabetic patients, consistently with an inhibitory effect of GLP-1 on renin secretion (68, 69)

Castellanos V, Workneh H, Malik A, Mehta B

Whether greater weight loss relative to semaglutide alone can be achieved with longer exposure to and different ratios of amylin-semaglutide combinations remains uncertain

Designed to balance blood sugar levels in patients with type 2 diabetes, glucagon-like peptide-1 (GLP-1) receptor agonists gained fame through a distinct and significant side effect: weight loss

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