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4.9 Addressing publication bias and negative outcomes While the majority of studies cited in this review report positive findings regarding the effects of natural compounds in AD models, the potential influence of publication bias must be acknowledged

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It may be related to the dose of the toxic drug used or the period of study observation.However, most of the current research results support the antioxidant stress effect of GPX1, so GPX1 is an important antioxidant in mammals