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The second is the evidence gap : because the blend has never been trialed as a fixed product, every dose, schedule and timeline here is inference from the two component literatures, not a proven blend outcome

Deeper treatments should be done by a licensed practitioner

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The ongoing clinical trials of oral SERDs primarily focus on identifying subpopulations with potential benefits following CDK4/6 inhibitor failure, investigating the efficacy of SERDs in combination with CDK4/6 inhibitors as first-line therapy, and reducing mortality rates among high-risk populations during the adjuvant stage

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