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Contra indicaciones y efectos secundarios Pese a ser un suplemento muy seguro, si nos excedemos de la dosis recomendada puede provocarnos cambios de humor, leves dolores de cabeza y problemas para conciliar el sueo, aunque rara vez suele darse

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Clinicians might consider berberine as an adjunct in patients with metabolic syndrome or hyperlipidemia who require extra risk factor reduction or cannot tolerate higher doses of standard drugs

[DOI] [PubMed] [Google Scholar] Sher M.R., Steven G.C., Romett J.L., Pien G., LeBenger K., Messina J.C., et al

Now, here's the clinically important implication, right