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A few commenters recommended that CMS consider making data submission to the repository mandatory by relying on its authority at section 1121 of the Act to establish a uniform system for the reporting, of discharge and bill data by facilities and organizations, in addition to general CMS authorities related to organizations enrolled in Medicare

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Even so, it comes with notable side effects when you consider the injectable form

For example, increased levels of GSH and GSH related systems in cancer have been employed as a basis for anticancer prodrug activation, anticancer drug delivery and anticancer drug development

doi: 10.1016/j.fbio.2020.100532 129