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found that lower fecal counts of Bifidobacterium in depressed patients than that in healthy controls, suggesting that Bifidobacterium plays an important role in the pathogenesis of depression ( Bifidobacterium can successfully inhibit elevated HPA axis and depression-like behaviors (Messaoudi et al., 2011)

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(9) This and other hormonal disruptions from lack of sleep can also lead to an increased appetite and increased cravings for sugar, salt, or refined carbohydrates