The Keap1Nrf2 proteinprotein interaction: a suitable target for small molecules
Early results from ongoing clinical studies are indicating the GLP-1 medications may successfully treat numerous other conditions including non-alcoholic fatty liver disease (known as metabolic dysfunction-associated steatohepatitis or MASH), sleep apnea, heart failure, diabetic kidney disease and Alzheimers disease
Nordlund JJ, Boissy RE
CrossRef Leptin Promotes White Adipocyte Browning by Inhibiting the Hh Signaling Pathway Jie Wang, Jing Ge, Haigang Cao, Xiaoyu Zhang, Yuan Guo, Xiao Li, Bo Xia, Gongshe Yang, Xine Shi Cells.2019
Additionally, increasing government initiatives focused on obesity management and supportive regulatory frameworks are facilitating faster drug approvals and market penetration