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Metabolite profiling reveals normal metabolic control in carriers of mutations in the glucokinase gene (MODY2)
We encourage patients to be transparent and detailed, as this can help establish realistic expectations
However, blood pressure and mood changes should be monitored regularly, and your healthcare provider should oversee the combination to ensure safety and efficacy for your specific health profile
In the SELECT trial, semaglutide reduced major adverse cardiovascular events in patients with overweight or obesity and established atherosclerotic cardiovascular disease without diabetes [16]
Pregnant patients or those planning pregnancy should not use either medication, though the reasoning differs (Metformin for potential effects on fetal development, Retatrutide due to insufficient safety data)
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