It happens when there are too many free radicals and not enough antioxidants
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However, natural glutathione levels can decline due to aging, stress, poor diet, illness, pollution, and lifestyle factors, which is why dietary support and supplementation have gained attention
& Allison, J
Very long-term continuous use (months to years) is not well-characterized and should be undertaken only with appropriate oversight, full tracking, and clear research objectives that justify the extended duration