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We have seen this happen, and this can be particularly problematic if your kidney function is already lower due to CKD." Patients with advanced CKD (eGFR between 1530 mL/min/1.73 m) or end-stage kidney disease (eGFR below 15 mL/min/1.73 m) require close monitoring since clinical data in these groups is limited

10.1016/S0140-6736(71)92415-9

Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia

Together, these effects highlight the capacity of KD to preserve dopaminergic neurons by directly interfering with apoptotic signaling cascades in PD

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