2.2 The role of inflammation in endometriosis The coordinated action of macrophages, endometrial cells, endothelial cells, and activated lymphocytes, along with cytokines and chemokines, alters the abdominal immune microenvironment, facilitating pathological processes including cell proliferation, angiogenesis, lesion adhesion, growth, and invasion (34)
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Existing evidence suggests that a multi-leveled nerve microenvironment needs to be considered in schwannoma biology, as instructive cues from axons, inflammatory signals from macrophages and failed regenerative processes contribute to their formation and progression
2020;5 doi: 10.1172/jci.insight.133429
The son of a physician, botanist and chemist, Gmelin had a colourful beginning