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Table 14: Lipid-Modifying Effects of Rosuvastatin in Pediatric Patients 7 to 15 years of Age with HoFH After 6 Weeks % Difference estimates are based on transformations of the estimated mean difference in log LDL measurements between rosuvastatin and placebo using a mixed model adjusted for study period 1p=0.005, 2 p=0.003, 3 p=0.024 Primary Dysbetalipoproteinemia in Adults In a randomized, multicenter, double-blind cross-over study, 32 adult patients (27 with 2/2 and 4 with apo E mutation [Arg145Cys] with primary dysbetalipoproteinemia entered a 6-week dietary lead-in period on the NCEP Therapeutic Lifestyle Change (TLC) diet