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Curr Biol 12:10761085 Ma R, Hu J, Huang C, Wang M, Xiang J, Li G (2014) JAK2/STAT5/Bcl-xL signalling is essential for erythropoietin-mediated protection against apoptosis induced in PC12 cells by the amyloid -peptide A2535

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Following an apoptotic stimulus, Bax is activated and translocates to the mitochondria, where it undergoes a conformational change and inserts into the OMM

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What actually happens is a broader sympathomimetic activation that makes everything feel slightly heightened