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2018 Aug;20(8):1951-1956

Accinelli, C., Abbas, H.K., Vicari, A

6 Glutathione: central player in redox regulation and cellular defense Glutathione (GSH) is a tripeptide made of -glutamate, cysteine, and glycine that acts as the main non-enzymatic redox buffer in cells and plays a pivotal role in maintaining redox equilibrium

Notably, the signaling events downstream of these death receptors as well as Fas are known to trigger a distinct cell death called necroptosis or programmed necrosis [197]